The incidence of cervical cancer is very low in the United States. The American College of Obstetricians and Gynecologists’ (ACOG) recommendations suggest cervical cancer screening (Pap tests) beginning at age 21 regardless of when sexual activity may have begun. However, there are a few young women who will develop cervical cancer. This paper presents a case of invasive cervical cancer in a 19-year-old female who had previously received the HPV vaccine series.